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NERD domain-containing protein
The nuclease-related domain (NERD) is found in a range of bacterial as well as archaeal and plant proteins. It has distant similarity to endonucleases (hence its name) and its predicted secondary structure is helix - sheet - sheet - sheet - sheet - weak sheet/long loop - helix - sheet - sheet. The majority of NERD-containing proteins are single-domain, but in several cases proteins containing NERD have additional domains which in 75% of cases are involved in DNA processing [1]. [1]. 15055202. NERD: a DNA processing-related domain present in the anthrax. virulence plasmid, pXO1.. Grynberg M, Godzik A;. Trends Biochem Sci 2004;29:106-110. (from Pfam)
nuclease-related domain-containing protein
nuclease-related domain (NERD)-containing protein belongs to the PDDEXK nuclease superfamily whose members function as endonucleases
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