Protein Family Models for Protein (Select 1912411055) - Protein Family Models

Select item 4252901.

tRNA pseudouridylate synthase B C-terminal domain

This C-terminal region is found on a subset of TruB_B protein family members Pfam:PF01509. It is found from bacteria and archaea to fungi, plants and human. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF027523.5
Method:: HMM

Select item 4132352.

TruB family pseudouridylate synthase (N terminal domain)

Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes TruB, a pseudouridylate synthase that specifically converts uracil 55 to pseudouridine in most tRNAs. This family also includes Cbf5p that modifies rRNA [2]. [1]. 7489483. Purification, cloning, and properties of the tRNA psi 55. synthase from Escherichia coli.. Nurse K, Wrzesinski J, Bakin A, Lane BG, Ofengand J;. RNA 1995;1:102-112.. [2]. 9472021. The box H + ACA snoRNAs carry Cbf5p, the putative rRNA. pseudouridine synthase.. Lafontaine DLJ, Bousquet-Antonelli C, Henry Y, Caizergues-Ferrer. M, Tollervey D;. Genes Dev 1998;12:527-537. (from Pfam)

GO Terms:

Biological Process:: RNA processing (GO:0006396)

Date:: 2024-08-14

Family Accession:: NF013660.5
Method:: HMM

Select item 4039323.

new record, indexing in progress

Family Accession:

Select item 3896024.

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Family Accession:

Select item 3646515.

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Family Accession:

Select item 3477286.

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Family Accession:

Select item 3269807.

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Family Accession:

Select item 3165548.

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Family Accession:

Select item 1812699.

tRNA pseudouridine(55) synthase TruB

tRNA pseudouridine(55) synthase TruB catalyzes the isomerization of uridine to pseudouridine at position 55 in the psi GC loop of transfer RNAs

Date:: 2022-08-29

Family Accession:: 10118778
Method:: Sparcle

Select item 16059810.

new record, indexing in progress

Family Accession:

Select item 14678711.

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Family Accession:

Select item 1845312.

tRNA pseudouridine(55) synthase TruB

TruB, the tRNA pseudouridine 55 synthase, converts uracil to pseudouridine in the T loop of most tRNAs in all three domains of life. This model is built on a seed alignment of bacterial proteins only, but may also hit organellar proteins.

Gene:: truB

GO Terms:

Biological Process:: pseudouridine synthesis (GO:0001522)

Molecular Function:: RNA binding (GO:0003723)

Biological Process:: RNA modification (GO:0009451)

Molecular Function:: pseudouridine synthase activity (GO:0009982)

Date:: 2024-05-15

Family Accession:: TIGR00431.1
Method:: HMM

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