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efflux RND transporter permease subunit
Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer [1]. [1]. 12374972. Crystal structure of bacterial multidrug efflux transporter. AcrB.. Murakami S, Nakashima R, Yamashita E, Yamaguchi A;. Nature 2002;419:587-593. (from Pfam)
Protein export membrane protein
This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC [1]. SecD and SecF are required to maintain a proton motive force [2]. [1]. 9694879. SecDF of Bacillus subtilis, a molecular Siamese twin required. for the efficient secretion of proteins.. Bolhuis A, Broekhuizen CP, Sorokin A, van Roosmalen ML, Venema. G, Bron S, Quax WJ, van Dijl JM;. J Biol Chem 1998;273:21217-21224.. [2]. 8112309. SecD and SecF are required for the proton electrochemical. gradient stimulation of preprotein translocation.. Arkowitz RA, Wickner W;. EMBO J 1994;13:954-963. (from Pfam)
CusA/CzcA family heavy metal efflux RND transporter
This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of Pfam HMM PF00873.
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