Protein Family Models

Date:

2024-08-14

Members of this family are found in within O-antigen biosynthesis clusters in Gram negative bacteria, where they are predicted to function as glycosyltransferases [1,2]. [1]. 15109730. The O-antigen gene cluster of Shigella boydii O11 and functional. identification of its wzy gene.. Tao J, Feng L, Guo H, Li Y, Wang L;. FEMS Microbiol Lett. 2004;234:125-132.. [2]. 16055280. Structural and genetic characterization of the Shigella boydii. type 18 O antigen.. Feng L, Senchenkova SN, Wang W, Shashkov AS, Liu B, Shevelev SD,. Liu D, Knirel YA, Wang L;. Gene. 2005;355:79-86. (from Pfam)

Date:

2024-08-14

Date:

2024-08-14

Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis [1][2]. [1]. 9515923. Characterization of the gene cassette required for biosynthesis. of the (alpha1-->6)-linked N-acetyl-D-mannosamine-1-phosphate. capsule of serogroup A Neisseria meningitidis.. Swartley JS, Liu LJ, Miller YK, Martin LE, Edupuganti S,. Stephens DS;. J Bacteriol. 1998;180:1533-1539.. [2]. 11953367. Novel Aeromonas hydrophila PPD134/91 genes involved in O-antigen. and capsule biosynthesis.. Zhang YL, Arakawa E, Leung KY;. Infect Immun. 2002;70:2326-2335. (from Pfam)

Date:

2024-08-14

Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. (from Pfam)

Date:

2024-08-14

Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. (from Pfam)

Date:

2024-08-14