Protein Family Models for Protein (Select 1986456654) - Protein Family Models

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Items: 5

Select item 4172751.

Na+/H+ antiporter NhaA

This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyse the exchange of H+ for Na+ in a manner that is highly dependent on the pH [1]. [1]. 1657980. Expression of a sodium proton antiporter (NhaA) in Escherichia. coli is induced by Na+ and Li+ ions.. Karpel R, Alon T, Glaser G, Schuldiner S, Padan E;. J Biol Chem 1991;266:21753-21759. (from Pfam)

GO Terms:

Biological Process:: sodium ion transport (GO:0006814)

Biological Process:: regulation of pH (GO:0006885)

Cellular Component:: membrane (GO:0016020)

Date:: 2024-08-14

Family Accession:: NF018648.5
Method:: HMM

Select item 3945882.

new record, indexing in progress

Family Accession:

Select item 3523493.

new record, indexing in progress

Family Accession:

Select item 434614.

Na+/H+ antiporter NhaA

Na+/H+ antiporter NhaA extrudes sodium in exchange for external protons

Date:: 2018-04-12

Family Accession:: 10006841
Method:: Sparcle

Select item 219285.

Na+/H+ antiporter NhaA

These proteins are members of the NhaA Na+:H+ Antiporter (NhaA) Family (TC. 2.A.33). The Escherichia coli NhaA protein probably functions in the regulation of the internal pH when the external pH is alkaline. It also uses the H+ gradient to expel Na+ from the cell. Its activity is highly pH dependent. Only the E. coli protein is functionally and structurally well characterized.