Protein Family Models for Protein (Select 2083981866) - Protein Family Models

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Items: 4

Select item 4173291.

sigma factor-like helix-turn-helix DNA-binding protein

Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif [1]. [1]. 11931761. Structure of the bacterial RNA polymerase promoter specificity. sigma subunit.. Campbell EA, Muzzin O, Chlenov M, Sun JL, Olson CA, Weinman O,. Trester-Zedlitz ML, Darst SA;. Mol Cell 2002;9:527-539. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: DNA-binding transcription factor activity (GO:0003700)

Biological Process:: DNA-templated transcription initiation (GO:0006352)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Molecular Function:: sigma factor activity (GO:0016987)

Date:: 2024-08-14

Family Accession:: NF019886.5
Method:: HMM

Select item 3972672.

new record, indexing in progress

Family Accession:

Select item 3543923.

new record, indexing in progress

Family Accession:

Select item 522734.

sigma-70 family RNA polymerase sigma factor

This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several PFAM models hit segments of these sequences including Sigma-70 region 2 (PF04542) and Sigma-70, region 4 (PF04545), but not always above their respective trusted cutoffs.

GO Terms: