Protein Family Models for Protein (Select 2102257293) - Protein Family Models

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Links from Protein

Items: 6

Select item 4140941.

YhjD/YihY/BrkB family envelope integrity protein

YhjD and YihY are paralogs in Escherichia coli K-12. YhjD appears to have a transporter-like function in transporting lipid IV-A, a precursor of lipopolysaccharide (LPS). Mutation of BrkB in Bordetella pertussis increases serum resistance, which has led to it being called a virulence factor, but the finding would be consistent with a housekeeping role in cell envelope maintenance.

Date:: 2024-08-14

Family Accession:: NF015587.5
Method:: HMM

Select item 3906222.

new record, indexing in progress

Family Accession:

Select item 3526663.

new record, indexing in progress

Family Accession:

Select item 3187654.

new record, indexing in progress

Family Accession:

Select item 1757035.

YihY/virulence factor BrkB family protein

YihY/virulence factor BrkB family protein similar to Bordetella pertussis BrkB, a virulence factor that is essential for resistance to complement-dependent killing by serum

Date:: 2024-06-28

Family Accession:: 10003440
Method:: Sparcle

Select item 224506.

YihY family inner membrane protein

Initial identification of members of this protein family was based on characterization of the yihY gene product as ribonuclease BN in Escherichia coli. This identification has been withdrawn, as the group now finds the homolog in E. coli of RNase Z is the true ribonuclease BN rather than a strict functional equivalent of RNase Z. Members of this subfamily include the largely uncharacterized BrkB (Bordetella resist killing by serum B) from Bordetella pertussis. Some members have an additional C-terminal domain. Paralogs from E. coli (yhjD) and Mycobactrium tuberculosis (Rv3335c) are part of a smaller, related subfamily that form their own cluster.

GO Terms: