Protein Family Models

This family represents a conserved region of approximately 180 residues within plant and bacterial monogalactosyldiacylglycerol (MGDG) synthase (EC:2.4.1.46). In Arabidopsis, there are two types of MGDG synthase which differ in their N-terminal portion: type A and type B [1]. [1]. 11553816. Two types of MGDG synthase genes, found widely in both 16:3 and. 18:3 plants, differentially mediate galactolipid syntheses in. photosynthetic and nonphotosynthetic tissues in Arabidopsis. thaliana.. Awai K, Marechal E, Block MA, Brun D, Masuda T, Shimada H,. Takamiya K, Ohta H, Joyard J;. Proc Natl Acad Sci U S A 2001;98:10960-10965. (from Pfam)

Date:

2024-08-14

The sequences scoring highest to this HMM are C-terminal regions of MurG enzymes (undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase), including the UDP-GlcNAc binding site. Those enzymes belong to glycosyltransferase family 28, but lower scoring members of this family include glycosyltransferases from other families that transfer different sugars.

Date:

2024-08-14

Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. (from Pfam)

Date:

2024-08-14