Protein Family Models for Protein (Select 2310787395) - Protein Family Models

Select item 4244411.

Date:: 2024-08-14

Family Accession:: NF025903.5
Method:: HMM

Select item 4116912.

This family includes the enzyme 4-oxalocrotonate tautomerase Swiss:Q01468 that catalyses the ketonisation of 2-hydroxymuconate to 2-oxo-3-hexenedioate. [1]. 7966298. Preliminary crystallographic analysis of 4-oxalocrotonate. tautomerase reveals the oligomeric structure of the enzyme.. Roper DI, Subramanya HS, Shingler V, Wigley DB;. J Mol Biol 1994;243:799-801. (from Pfam)

GO Terms:

Biological Process:: metabolic process (GO:0008152)

Molecular Function:: isomerase activity (GO:0016853)

Date:: 2024-08-14

Family Accession:: NF013522.5
Method:: HMM

Select item 4013933.

new record, indexing in progress

Family Accession:

Select item 3888514.

new record, indexing in progress

Family Accession:

Select item 3578035.

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Family Accession:

Select item 3472226.

new record, indexing in progress

Family Accession:

Select item 3427507.

2-hydroxymuconate tautomerase

2-hydroxymuconate tautomerase is also known as 4-oxalocrotonate tautomerase.

GO Terms:

Biological Process:: metabolic process (GO:0008152)

Molecular Function:: intramolecular oxidoreductase activity, interconverting keto- and enol-groups (GO:0016862)

Date:: 2024-05-07

Family Accession:: NF002571.1
Method:: HMM

Select item 3266368.

new record, indexing in progress

Family Accession:

Select item 3171369.

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Family Accession:

Select item 17866010.

new record, indexing in progress

Family Accession:

Select item 1636411.

2-hydroxymuconate tautomerase family protein

2-hydroxymuconate tautomerase (also called 4-oxalocrotonate tautomerase) is a homohexamer in which each monomer is very small, at about 62 amino acids. Pro-1 of the mature protein serves as a general base. The enzyme functions in meta-cleavage pathways of aromatic hydrocarbon catabolism. Because several Arg residues located near the active site in the crystal structure of Pseudomonas putida are not conserved among all members of this family, because the literature describes a general role in the isomerization of beta,gamma-unsaturated enones to their alpha,beta-isomers, and because some species contain fairly divergent paralogs, the family is regarded as not necessarily uniform in function.

GO Terms:

Molecular Function:: isomerase activity (GO:0016853)

Date:: 2024-06-21

Family Accession:: TIGR00013.1
Method:: HMM

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