Protein Family Models for Protein (Select 2335315656) - Protein Family Models

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Links from Protein

Items: 7

Select item 3975541.

This is a family of membrane signal serine endopeptidases which function in the processing of newly-synthesised secreted proteins. Peptidase S26 removes the hydrophobic, N-terminal, signal peptides as proteins are translocated across membranes. The active site residues take the form of a catalytic dyad that is Ser, Lys in subfamily S26A; the Ser is the nucleophile in catalysis, and the Lys is the general base. (from Pfam)

GO Terms:

Molecular Function:: serine-type endopeptidase activity (GO:0004252)

Biological Process:: signal peptide processing (GO:0006465)

Date:: 2024-07-08

Family Accession:: NF021981.4
Method:: HMM

Select item 3563902.

new record, indexing in progress

Family Accession:

Select item 3464633.

new record, indexing in progress

Family Accession:

Select item 3321614.

new record, indexing in progress

Family Accession:

Select item 3157635.

new record, indexing in progress

Family Accession:

Select item 1059126.

S26 family signal peptidase

S26 family signal peptidase is a membrane-bound serine protease which frees proteins tethered to inner or mitochondrial membranes by cleaving off signal peptides during polypeptide translocation

Date:: 2022-08-05

Family Accession:: 12106434
Method:: Sparcle

Select item 486747.

signal peptidase I

This HMM represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes.