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Links from Protein

Items: 7

1.

4Fe-4S cluster-binding domain-containing protein

This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich. (from Pfam)

Date:
2024-08-14
Family Accession:
NF024747.5
Method:
HMM
2.

radical SAM protein

Radical SAM proteins catalyse diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation. [1]. 11222759. Radical SAM, a novel protein superfamily linking unresolved. steps in familiar biosynthetic pathways with radical mechanisms:. functional characterization using new analysis and information. visualization methods.. Sofia HJ, Chen G, Hetzler BG, Reyes-Spindola JF, Miller NE;. Nucleic Acids Res 2001;29:1097-1106.. [2]. 17335281. Anaerobic sulfatase-maturating enzymes: radical SAM enzymes able. to catalyze in vitro sulfatase post-translational modification.. Benjdia A, Leprince J, Guillot A, Vaudry H, Rabot S, Berteau O;. J Am Chem Soc. 2007;129:3462-3463.. [3]. 16766528. A new type of bacterial sulfatase reveals a novel maturation. pathway in prokaryotes.. Berteau O, Guillot A, Benjdia A, Rabot S;. J Biol Chem. 2006;281:22464-22470. (from Pfam)

GO Terms:
Molecular Function:
catalytic activity (GO:0003824)
Molecular Function:
4 iron, 4 sulfur cluster binding (GO:0051539)
Date:
2024-09-08
Family Accession:
NF015983.5
Method:
HMM
3.
new record, indexing in progress
Family Accession:
4.
new record, indexing in progress
Family Accession:
5.
new record, indexing in progress
Family Accession:
6.
new record, indexing in progress
Family Accession:
7.

anaerobic ribonucleoside-triphosphate reductase activating protein

This enzyme is a member of the radical-SAM family (PF04055). It is often gene clustered with the class III (anaerobic) ribonucleotide triphosphate reductase (NrdD, TIGR02487) and presumably fulfills the identical function as NrdG [1,2] which utilizes S-adenosyl methionine, an iron-sulfur cluster and a reductant (dihydroflavodoxin) to produce a glycine-centered radical in NrdD.

GO Terms:
Biological Process:
2'-deoxyribonucleotide biosynthetic process (GO:0009265)
Biological Process:
positive regulation of oxidoreductase activity (GO:0051353)
Molecular Function:
4 iron, 4 sulfur cluster binding (GO:0051539)
Date:
2021-05-12
Family Accession:
TIGR02495.1
Method:
HMM
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