Protein Family Models

The function of this region is not clear, but it is found in many flagellar hook proteins, including FliD homologues ([1]). It is normally repeated, but is also apparently seen as a singleton. A conserved IN is seen at the centre of the motif. The diversity of these motifs makes it likely that some members of the family are not identified. [1]. 11230454. Molecular characterization of fliD gene encoding flagellar cap. and its expression among Clostridium difficile isolates from. different serogroups.. Tasteyre A, Karjalainen T, Avesani V, Delmee M, Collignon A,. Bourlioux P, Barc MC;. J Clin Microbiol 2001;39:1178-1183. (from Pfam)

Date:

2024-08-14

Flagellins polymerise to form bacterial flagella. There is some similarity between this family and Pfam:PF00669, particularly the motif NRFXSXIXXL. It has been suggested that these two regions associate [2] and this is shown to be correct as structurally this family forms an extended helix that interacts with Pfam:PF00700. [1]. 7648320. Spinning tails.. DeRosier DJ;. Curr Opin Struct Biol 1995;5:187-193.. [2]. 2190210. Flagellin as an object for supramolecular engineering.. Fedorov OV, Efimov AV;. Protein Eng 1990;3:411-413. (from Pfam)

Date:

2024-08-14

Flagellins polymerise to form bacterial flagella. This family includes flagellins and hook associated protein 3. Structurally this family forms an extended helix that interacts with Pfam:PF00700. [1]. 7648320. Spinning tails.. DeRosier DJ;. Curr Opin Struct Biol 1995;5:187-193. (from Pfam)

Date:

2024-08-14