Protein Family Models

Date:

2024-08-14

This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90. [1]. 18361456. Crystal structure of a novel non-Pfam protein AF1514 from. Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray. source.. Li Y, Bahti P, Shaw N, Song G, Chen S, Zhang X, Zhang M, Cheng. C, Yin J, Zhu JY, Zhang H, Che D, Xu H, Abbas A, Wang BC, Liu. ZJ;. Proteins 2008;71:2109-13. (from Pfam)

Date:

2024-08-14

Binds to sigma-B preventing the formation of an RNA polymerase holoenzyme

Gene:

rsbW

Date:

2020-10-26

This model describes the anti-sigma B factor also known as serine-protein kinase RsbW. Sigma B controls the general stress regulon in B subtilis and is activated by cell stresses such as stationary phase and heat shock. RsbW binds to sigma B and prevents formation of the transcription complex at the promoter.[1] RsbV (anti-anti-sigma factor) binds to RsbW to inhibit association with sigma B, however RsbW can phosphorylate RsbV, causing disassociation of the RsbV/RsbW complex.[2] Low ATP level or environmental stress causes the dephosphorylation of RsbV.[3]

Gene:

rsbW

Date:

2024-05-30

ATPase similar to histidine kinase domains

Date:

2016-05-13