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NACHT N-terminal Helical domain 5
NACHT-associated inactive Restriction Endonuclease 1
Anaphase-promoting complex subunit 4 WD40 domain
Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilise the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC, [1]. 12049731. The anaphase-promoting complex: proteolysis in mitosis and. beyond.. Peters JM;. Mol Cell. 2002;9:931-943.. [2]. 16896351. The anaphase promoting complex/cyclosome: a machine designed to. destroy.. Peters JM;. Nat Rev Mol Cell Biol. 2006;7:644-656.. [3]. 19584054. The transcription factor Atf1 binds and activates the APC/C. ubiquitin ligase in fission yeast.. Ors A, Grimaldi M, Kimata Y, Wilkinson CR, Jones N, Yamano H;. J Biol Chem. 2009;284:23989-23994. (from Pfam)
Eukaryotic translation initiation factor eIF2A
This is a family of eukaryotic translation initiation factors. [1]. 12133843. Characterization of mammalian eIF2A and identification of the. yeast homolog.. Zoll WL, Horton LE, Komar AA, Hensold JO, Merrick WC;. J Biol Chem. 2002;277:37079-37087. (from Pfam)
NACHT domain-containing protein
This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation [1]. This family is closely related to Pfam:PF00931. [1]. 10782090. The NACHT family - a new group of predicted NTPases implicated. in apoptosis and MHC transcription activation.. Koonin EV, Aravind L;. Trends Biochem Sci 2000;25:223-224. (from Pfam)
WD40 repeat-containing protein
WD40 domain-containing protein
protein containing domains COG5635, and WD40
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