Protein Family Models

Date:

2024-08-14

Rad51 is a DNA repair and recombination protein and is a homologue of the bacterial ATPase RecA protein. [1]. 16169964. Arabidopsis RAD51C gene is important for homologous. recombination in meiosis and mitosis.. Abe K, Osakabe K, Nakayama S, Endo M, Tagiri A, Todoriki S,. Ichikawa H, Toki S;. Plant Physiol. 2005;139:896-908. (from Pfam)

Date:

2024-08-14

RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyses an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination [1]. [1]. 7022448. recA protein of Escherichia coli promotes branch migration, a. kinetically distinct phase of DNA strand exchange.. Cox MM, Lehman IR;. Proc Natl Acad Sci U S A. 1981;78:3433-3437. (from Pfam)

Date:

2024-08-14

This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage.

Gene:

recA

Date:

2024-05-14

recombinase RecA catalyzes an ATP-dependent DNA strand-exchange reaction, which is a critical step in the repair of DNA double-strand breaks by homologous recombination

Date:

2024-05-19