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Links from Protein

Items: 3

1.

AIR carboxylase family protein

Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyse the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain. [1]. 10574791. Crystal structure of Escherichia coli PurE, an unusual mutase in. the purine biosynthetic pathway.. Mathews II, Kappock TJ, Stubbe J, Ealick SE;. Structure Fold Des 1999;7:1395-1406. (from Pfam)

GO Terms:
Biological Process:
'de novo' IMP biosynthetic process (GO:0006189)
Date:
2024-08-14

Family Accession:
NF012934.5
Method:
HMM

2.
new record, indexing in progress
Family Accession:
3.

5-(carboxyamino)imidazole ribonucleotide mutase

Phosphoribosylaminoimidazole carboxylase is a fusion protein in plants and fungi, but consists of two non-interacting proteins in bacteria, PurK and PurE. This model represents PurK, an N5-CAIR mutase.

Gene:
purE
GO Terms:
Molecular Function:
phosphoribosylaminoimidazole carboxylase activity (GO:0004638)
Biological Process:
'de novo' IMP biosynthetic process (GO:0006189)
Biological Process:
purine ribonucleotide biosynthetic process (GO:0009152)
Cellular Component:
phosphoribosylaminoimidazole carboxylase complex (GO:0009320)
Date:
2024-05-28

Family Accession:
TIGR01162.1
Method:
HMM

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