Protein Family Models for Protein (Select 2705739216) - Protein Family Models

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Links from Protein

Items: 6

Select item 4209691.

alpha/beta fold hydrolase

This family contains alpha/beta hydrolase enzymes of diverse specificity. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024109.5
Method:: HMM

Select item 4114992.

thioesterase domain-containing protein

Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates. There are also modules within the peptide synthetases that also share this similarity. With respect to antibiotic production, thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic. Thioesterases (non-integrated) have molecular masses of 25-29 kDa. [1]. 9560421. Genetic evidence for a role of thioesterase domains, integrated. in or associated with peptide synthetases, in non-ribosomal. peptide biosynthesis in Bacillus subtilis.. Schneider A, Marahiel MA;. Arch Microbiol 1998;169:404-410. (from Pfam)

GO Terms:

Biological Process:: biosynthetic process (GO:0009058)

Date:: 2024-08-14

Family Accession:: NF013166.5
Method:: HMM

Select item 4113293.

alpha/beta fold hydrolase

This catalytic domain is found in a very wide range of enzymes. [1]. 1409539. The alpha/beta hydrolase fold. Ollis DL, Cheah E, Cygler M, Dijkstra B, Frolow F, Franken SM,. Harel M, Remington SJ, Silman I, Schrag J, Sussman JL,. Verschueren KHG, Goldman A;. Protein Eng 1992;5:197-211. (from Pfam)