Protein Family Models for Protein (Select 2710794396) - Protein Family Models

Select item 4263201.

methyltransferase domain-containing protein

This family appears to have methyltransferase activity. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025217.5
Method:: HMM

Select item 4232842.

methyltransferase domain-containing protein

This family appears to be a methyltransferase domain. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025033.5
Method:: HMM

Select item 4189883.

RNA cap guanine-N2 methyltransferase

RNA cap guanine-N2 methyltransferases such as Schizosaccharomyces pombe Tgs1 and Giardia lamblia Tgs2 catalyse methylation of the exocyclic N2 amine of 7-methylguanosine [1]. [1]. 17284461. Biochemical and Genetic Analysis of RNA Cap Guanine-N2. Methyltransferases from Giardia lamblia and Schizosaccharomyces. pombe.. Hausmann S, Ramirez A, Schneider S, Schwer B, Shuman S;. Nucleic Acids Res. 2007; [Epub ahead of print] (from Pfam)

GO Terms:

Biological Process:: RNA methylation (GO:0001510)

Molecular Function:: methyltransferase activity (GO:0008168)

Biological Process:: 7-methylguanosine cap hypermethylation (GO:0036261)

Date:: 2024-08-14

Family Accession:: NF020996.5
Method:: HMM

Select item 4165624.

tRNA (Uracil-5-)-methyltransferase

This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalysed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity [1]. [1]. 12003492. Dual function of the tRNA(m(5)U54)methyltransferase in tRNA. maturation.. Johansson MJ, Bystrom AS;. RNA 2002;8:324-335. (from Pfam)

GO Terms:

Biological Process:: RNA processing (GO:0006396)

Molecular Function:: RNA methyltransferase activity (GO:0008173)

Date:: 2024-08-14

Family Accession:: NF017743.5
Method:: HMM

Select item 4156095.

methyltransferase

This domain is found in ribosomal RNA small subunit methyltransferase C (eg Swiss:P44453) as well as other methyltransferases (eg Swiss:Q53742). (from Pfam)

GO Terms:

Molecular Function:: methyltransferase activity (GO:0008168)

Date:: 2024-08-14

Family Accession:: NF017026.5
Method:: HMM

Select item 4136736.

Met-10+ like-protein

The methionine-10 mutant allele of N. crassa codes for a protein of unknown function, Swiss:O27901. However, homologous proteins have been found in yeast (Swiss:P38793) suggesting this protein may be involved in methionine biosynthesis, transport and/or utilisation [1]. [1]. 7557397. Sequence of the met-10+ locus of Neurospora crassa: homology to. a sequence of unknown function in Saccharomyces cerevisiae. chromosome 8.. Chow CM, Kang S, Metzenberg RL, RajBhandary UL;. Gene 1995;162:111-115. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF014527.5
Method:: HMM

Select item 4116047.

TRAM domain-containing protein

This small domain has no known function. However it may perform a nucleic acid binding role (Bateman A. unpublished observation). [1]. 11313137. TRAM, a predicted RNA-binding domain, common to tRNA uracil. methylation and adenine thiolation enzymes.. Anantharaman V, Koonin EV, Aravind L;. FEMS Microbiol Lett 2001;197:215-221. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF014047.5
Method:: HMM

Select item 4030098.