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HNH endonuclease
This domain is related to other HNH domain families such as Pfam:PF01844. Suggesting that these proteins have a nucleic acid cleaving function. (from Pfam)
group II intron maturase-specific domain-containing protein
This region is found mainly in various bacterial and archaeal species, but a few members of this family are expressed by fungal and chlamydomonal species. It has been implicated in the binding of intron RNA during reverse transcription and splicing [1]. [1]. 11959575. Presence of a group II intron in a multiresistant Serratia. marcescens strain that harbors three integrons and a novel gene. fusion.. Centron D, Roy PH;. Antimicrob Agents Chemother 2002;46:1402-1409. (from Pfam)
His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity [4]. Named family as HNH. [1]. 7817395. Amino acid sequence motif of group I intron endonucleases is. conserved in open reading frames of group II introns.. Shub DA, Goodrich-Blair H, Eddy SR;. Trends Biochem Sci 1994;19:402-404.. Extended HNH family. [2]. 9358175. Statistical modeling and analysis of the LAGLIDADG family of. site-specific endonucleases and identification of an intein that. encodes a site-specific endonuclease of the HNH family.. Dalgaard JZ, Klar AJ, Moser MJ, Holley WR, Chatterjee A, Mian. IS;. Nucleic Acids Res 1997;25:4626-4638.. Named family as EX1HH-HX3H. [3]. 7920259. Self-splicing group I and group II introns encode homologous. (putative) DNA endonucleases of a new family.. Gorbalenya AE;. Protein Sci 1994;3:1117-1120.. [4]. 27131500. Biochemical characterization of a thermostable HNH endonuclease. from deep-sea thermophilic bacteriophage GVE2.. Zhang L, Huang Y, Xu D, Yang L, Qian K, Chang G, Gong Y, Zhou X,. Ma K;. Appl Microbiol Biotechnol. 2016;100:8003-8012. (from Pfam)
reverse transcriptase domain-containing protein
A reverse transcriptase gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. Reverse transcriptases occur in a variety of mobile elements, including retrotransposons, retroviruses, group II introns, bacterial msDNAs, hepadnaviruses, and caulimoviruses. [1]. 1698615. Origin and evolution of retroelements based upon their reverse. transcriptase sequences.. Xiong Y, Eickbush TH;. EMBO J 1990;9:3353-3362. (from Pfam)
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