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MATE family efflux transporter
MATE (Multi Antimicrobial Extrusion), 2.A.66.1 in Transporter Classification Database, is a widely distributed transporter family that includes both human proteins and bacterial antibiotic resistance efflux transporters.
The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS.
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