Protein Family Models for Protein (Select 2713467496) - Protein Family Models

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Items: 5

Select item 4259391.

SpaA isopeptide-forming pilin-related protein

This HMM described a domain that is often repeated in pilins such as SpaA, and that often forms isopeptide bonds cross-linking amino acid side chains, giving the pilins added strength.

Date:: 2024-08-14

Family Accession:: NF037639.5
Method:: HMM

Select item 4124892.

LPXTG cell wall anchor motif

Date:: 2024-08-14

Family Accession:: NF012948.5
Method:: HMM

Select item 4064243.

new record, indexing in progress

Family Accession:

Select item 3892884.

new record, indexing in progress

Family Accession:

Select item 1409165.

LPXTG cell wall anchor domain-containing protein

This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region.

GO Terms: