Protein Family Models for Protein (Select 2729037042) - Protein Family Models

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Items: 4

Select item 3990771.

new record, indexing in progress

Family Accession:

Select item 3974992.

new record, indexing in progress

Family Accession:

Select item 3892633.

new record, indexing in progress

Family Accession:

Select item 1430044.

Cu(I)-responsive transcriptional regulator

This HMM represents the copper-, silver- and gold- (I) responsive transcriptional activator of the gamma proteobacterial copper efflux system [1]. This protein is a member of the MerR family of transcriptional activators (PF00376) and contains a distinctive pattern of cysteine residues in its metal binding loop, Cys-X7-Cys. This family also lacks a conserved cysteine at the N-terminal end of the dimerization helix which is required for the binding of divalent metals such as zinc; here it is replaced by a serine residue [2].