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Links from Protein

Items: 4

1.

Kynureninase C-terminal domain

Date:
2024-08-14
Family Accession:
NF047213.1
Method:
HMM
2.

aminotransferase class V-fold PLP-dependent enzyme

This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-. (from Pfam)

Date:
2024-08-14
Family Accession:
NF012488.5
Method:
HMM
3.
new record, indexing in progress
Family Accession:
4.

kynureninase

This HMM describes kynureninase, a pyridoxal-phosphate enzyme. Kynurinine is a Trp breakdown product and a precursor for NAD. In Chlamydia psittaci, an obligate intracellular pathogen, kynureninase makes anthranilate, a Trp precursor, from kynurenine. This counters the tryptophan hydrolysis that occurs in the host cell in response to the pathogen.

Gene:
kynU
GO Terms:
Cellular Component:
cytoplasm (GO:0005737)
Biological Process:
tryptophan catabolic process (GO:0006569)
Biological Process:
NAD biosynthetic process (GO:0009435)
Molecular Function:
pyridoxal phosphate binding (GO:0030170)
Molecular Function:
kynureninase activity (GO:0030429)
Date:
2024-05-29
Family Accession:
TIGR01814.1
Method:
HMM
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