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winged helix-turn-helix domain-containing protein
response regulator
This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. [1]. 7699720. Response regulators of bacterial signal transduction systems:. selective domain shuffling during evolution.. Pao GM, Saier MH;. J Mol Evol 1995;40:136-154. (from Pfam)
copper response regulator transcription factor PcoR
PcoR is part of a two-component sensor kinase/response regulator system. It is phosphorylated by PcoS.
heavy metal response regulator transcription factor
Members of this family contain a response regulator receiver domain (Pfam:PF00072) and an associated transcriptional regulatory region (Pfam:PF00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system.
response regulator transcription factor PcoR
two-component system response regulator transcription factor PcoR binds DNA upon phosphorylation and functions as transcriptional regulator in the two-component regulatory system PcoS/PcoR, which plays a role activating the copper resistance gene operon pcoABCD
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