Protein Family Models for Protein (Select 488100125) - Protein Family Models

Select item 4219501.

Glyoxalase-like domain

This domain is related to the Glyoxalase domain Pfam:PF00903. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024093.5
Method:: HMM

Select item 4114182.

VOC family protein

Date:: 2024-08-14

Family Accession:: NF013098.5
Method:: HMM

Select item 3998473.

new record, indexing in progress

Family Accession:

Select item 3894344.

new record, indexing in progress

Family Accession:

Select item 3574475.

new record, indexing in progress

Family Accession:

Select item 3467206.

new record, indexing in progress

Family Accession:

Select item 3422777.

FosBx1 family fosfomycin resistance bacillithiol transferase

Members of this family, found in Bacillus cereus and related species that synthesis bacillithiol rather than glutathione, are VOC family thiol transferases. They provide resistance to the antibiotic fosfomycin by transferring either bacillithiol or cysteine (but not glutathione) to fosfomycin, leaving it inactive. Note that this family is drawn rather narrowly, and several such families, all non-overlapping, appear in B. cereus and its close relatives. This family includes proteins that have been named FosBx1 (although the original source of that name is hard to trace), and the protein studied crystallographically by Thompson, et al. (see PMID:24004181).

Gene:: fosB

Date:: 2023-02-14

Family Accession:: NF041541.1
Method:: HMM

Select item 1835038.

metallothiol transferase FosB

Catalyzes resistance to fosfomycin by the addition of a thiol cofactor

Gene:: fosB

Date:: 2020-10-26

Family Accession:: NF003152.0
Method:: HMM

Select item 1640289.

new record, indexing in progress

Family Accession:

Select item 16372510.

FosB/FosD family fosfomycin resistance bacillithiol transferase

Gene:: fosB

Date:: 2020-10-26

Family Accession:: NF000493.1
Method:: HMM

Select item 13631611.

metallothiol transferase FosB

metallothiol transferase FosB confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin

Date:: 2019-08-06

Family Accession:: 10012138
Method:: Sparcle

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