Protein Family Models for Protein (Select 489012065) - Protein Family Models

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Items: 5

Select item 4112441.

phosphoribosyltransferase family protein

This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7, Swiss:P07672. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase Swiss:P51900. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8 Swiss:P36766. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1 Swiss:P09329. Amidophosphoribosyltransferase EC:2.4.2.14 Swiss:P00496. Orotate phosphoribosyl-transferase EC:2.4.2.10 Swiss:P11172. Uracil phosphoribosyl-transferase EC:2.4.2.9 Swiss:P25532. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22 Swiss:P00501. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain [1]. [1]. 17143579. Functional characterization of a gene encoding a dual domain for. uridine kinase and uracil phosphoribosyltransferase in. Arabidopsis thaliana.. Islam MR, Kim H, Kang SW, Kim JS, Jeong YM, Hwang HJ, Lee SY,. Woo JC, Kim SG;. Plant Mol Biol. 2007;63:465-477. (from Pfam)

GO Terms:

Biological Process:: nucleoside metabolic process (GO:0009116)

Date:: 2024-08-14

Family Accession:: NF012383.5
Method:: HMM

Select item 3881922.

new record, indexing in progress

Family Accession:

Select item 3481013.

new record, indexing in progress

Family Accession:

Select item 2519264.

orotate phosphoribosyltransferase

orotate phosphoribosyltransferase catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)

Date:: 2022-08-18

Family Accession:: 10011447
Method:: Sparcle

Select item 191455.

orotate phosphoribosyltransferase

Orotate phosphoribosyltransferase (OPRTase) is involved in the biosynthesis of pyrimidine nucleotides. Alpha-D-ribosyldiphosphate 5-phosphate (PRPP) and orotate are utilized to form pyrophosphate and orotidine 5'-monophosphate (OMP) in the presence of divalent cations, preferably Mg2+. In a number of eukaryotes, this protein is fused to a domain that catalyses the reaction (EC 4.1.1.23). The combined activity of EC 2.4.2.10 and EC 4.1.1.23 is termed uridine 5'-monophosphate synthase. The conserved Lys (K) residue at position 101 of the seed alignment has been proposed as the active site for the enzyme.