Protein Family Models for Protein (Select 491113274) - Protein Family Models

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Items: 5

Select item 4110211.

KDPG and KHG aldolase

This family includes the following members: 4-hydroxy-2-oxoglutarate aldolase (KHG-aldolase) Phospho-2-dehydro-3-deoxygluconate aldolase (KDPG-aldolase) (from Pfam)

GO Terms:

Molecular Function:: lyase activity (GO:0016829)

Date:: 2024-08-14

Family Accession:: NF013263.5
Method:: HMM

Select item 3882422.

new record, indexing in progress

Family Accession:

Select item 3482703.

new record, indexing in progress

Family Accession:

Select item 1413594.

bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase

2-deydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) is an enzyme of the Entner-Doudoroff pathway. This aldolase has another function, 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) shown experimentally in Escherichia coli and Pseudomonas putida

Gene:: eda

GO Terms:

Molecular Function:: 2-dehydro-3-deoxy-phosphogluconate aldolase activity (GO:0008675)

Molecular Function:: 4-hydroxy-2-oxoglutarate aldolase activity (GO:0008700)

Biological Process:: Entner-Doudoroff pathway through 6-phosphogluconate (GO:0009255)

Date:: 2024-06-14

Family Accession:: TIGR01182.1
Method:: HMM

Select item 814995.

bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase

bifunctional 4-hydroxy-2-oxoglutarate (KHG) aldolase/2-dehydro-3-deoxy-phosphogluconate (KDPG) aldolase is involved in the degradation of glucose via the Entner-Doudoroff pathway; catalyzes the reversible, stereospecific retro-aldol cleavage of KDPG to pyruvate and D-glyceraldehyde-3-phosphate