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5'/3'-nucleotidase SurE
E. coli cells with the surE gene disrupted are found to survive poorly in stationary phase [1]. It is suggested that SurE may be involved in stress response. Yeast also contains a member of the family Swiss:P38254. Swiss:P30887 can complement a mutation in acid phosphatase, suggesting that members of this family could be phosphatases. [1]. 7928962. A new gene involved in stationary-phase survival located at 59. minutes on the Escherichia coli chromosome. Li C, Ichikawa JK, Ravetto JJ, Kuo HC, Fu JC, Clarke S;. J Bacteriol 1994;176:6015-6022.. [2]. 1423722. Complementation of Saccharomyces cerevisiae acid phosphatase. mutation by a genomic sequence from the yeast Yarrowia. lipolytica identifies a new phosphatase.. Treton BY, Le Dall MT, Gaillardin CM;. Curr Genet 1992;22:345-355. (from Pfam)
5'/3'-nucleotidase SurE (survival protein E) is a metal ion-dependent phosphatase that plays a role in stress response
SurE, a metal-dependent phosphatase, is a stationary phase survival protein with activities against 3'-ribonucleotides, 5'-ribonucleotides, and polyphosphate.
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