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sporulation transcriptional regulator SpoIIID
This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif. [1]. 7867944. Cloning and characterization of a Bacillus thuringiensis homolog. of the spoIIID gene from Bacillus subtilis.. Yoshisue H, Ihara K, Nishimoto T, Sakai H, Komano T;. Gene. 1995;154:23-29. (from Pfam)
sporulation transcriptional regulator SpoIIID regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor, sigma K
Members of this protein are the transcriptional regulator SpoIIID, or stage III sporulation protein D. It is present in genomes if and only if the species is capable of endospore formation as occurs in the model species Bacillus subtilis. SpoIIID is a DNA binding protein that, in B. subtilis, downregulates many genes but also turns on ten genes.
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