Protein Family Models for Protein (Select 494073711) - Protein Family Models

Select item 3997981.

The exact function of this domain is not clear, but it frequently occurs as an N-terminal region of transposase 3 or IS3 family of insertion elements. (from Pfam)

Date:: 2023-12-12

Family Accession:: NF025079.4
Method:: HMM

Select item 3902212.

Tn3 family transposase

This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases [2]. [1]. 6262296. Purification of the Tn3 transposase and analysis of its binding. to DNA.. Fennewald MA, Gerrard SP, Chou J, Casadaban MJ, Cozzarelli NR;. J Biol Chem 1981;256:4687-4690.. [2]. 8932514. Catalytic center quest: comparison of transposases belonging to. the Tn3 family reveals an invariant triad of acidic amino acid. residues.. Yurieva O, Nikiforov V;. Biochem Mol Biol Int 1996;38:15-20. (from Pfam)

GO Terms:

Molecular Function:: transposase activity (GO:0004803)

Biological Process:: DNA transposition (GO:0006313)

Date:: 2024-04-03

Family Accession:: NF013676.4
Method:: HMM

Select item 3638733.