Protein Family Models

This is a family of proteins of unknown function found in viruses. This family is a P-loop member whose proteins are thought to be SF3 helicases, which are involved in replication initiation. (from Pfam)

Date:

2024-08-14

Based on Bacteroides thetaiotaomicron gene BT_4228, a putative uncharacterized protein As seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2231), It appears to be upregulated in the presence of host or other bacterial species vs when in culture [1,2]. [1]. 15790854. Glycan foraging in vivo by an intestine-adapted bacterial. symbiont.. Sonnenburg JL, Xu J, Leip DD, Chen CH et al. Science 2005 Mar 25;307(5717):1955-9.. [2]. 16735464. A hybrid two-component system protein of a prominent human gut. symbiont couples glycan sensing in vivo to carbohydrate. metabolism.. Sonnenburg ED, Sonnenburg JL, Manchester JK, Hansen EE et al.. Proc Natl Acad Sci U S A 2006 Jun 6;103(23):8834-9. (from Pfam)

Date:

2024-08-14

Members of this family are related to VapE (virulence-associated protein E) of Dichelobacter nodosus.

Date:

2024-08-14