Protein Family Models

Date:

2024-08-14

This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria [1]. [1]. 10632887. The thermostable alpha-L-rhamnosidase RamA of Clostridium. stercorarium: biochemical characterization and primary structure. of a bacterial alpha-L-rhamnoside hydrolase, a new type of. inverting glycoside hydrolase.. Zverlov VV, Hertel C, Bronnenmeier K, Hroch A, Kellermann J,. Schwarz WH;. Mol Microbiol 2000;35:173-179. (from Pfam)

Date:

2024-08-14

This domain is found on the N-terminal of some glycogen debranching enzymes and is usually followed by the GDE_C (PF06202) and in this sense it is analogous (but probably not homologous) to the GDE_N (PF12439). Its exact function is unknown (from Pfam)

Date:

2024-08-14

This family includes human glycogen branching enzyme Swiss:P35573. This enzyme contains a number of distinct catalytic activities. It has been shown for the yeast homologue Swiss:O93808 that mutations in this region disrupt the enzymes Amylo-alpha-1,6-glucosidase (EC:3.2.1.33). [1]. 11375985. Identification of the catalytic residues of bifunctional. glycogen debranching enzyme.. Nakayama A, Yamamoto K, Tabata S;. J Biol Chem 2001;276:28824-28828. (from Pfam)

Date:

2024-08-14

Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with Pfam:PF07492 in fungi. [1]. 12782117. Biochemical and genomic regulation of the trehalose cycle in. yeast: review of observations and canonical model analysis.. Voit EO;. J Theor Biol 2003;223:55-78. (from Pfam)

Date:

2024-08-14