Protein Family Models for Protein (Select 505065921) - Protein Family Models

Select item 3913881.

This domain is found associated with the Pfam tRNA synthetase class II domain (Pfam:PF00587) and represents the N-terminal domain of seryl-tRNA synthetase. [1]. 8654381. The crystal structure of the ternary complex of T.thermophilus. seryl-tRNA synthetase with tRNA(Ser) and a seryl-adenylate. analogue reveals a conformational switch in the active site.. Cusack S, Yaremchuk A, Tukalo M;. EMBO J 1996;15:2834-2842. (from Pfam)

Date:: 2024-04-03

Family Accession:: NF014458.4
Method:: HMM

Select item 3899602.

aminoacyl--tRNA ligase-related protein

This HMM finds multiple types of aminoacyl--tRNA ligase, such as those for Thr, Pro, His, and Ser in Escherichia coli. Because equivalog-level HMMs exist to identify full-length members of the tRNA ligase families, any protein receiving annotation from this HMM is most likely to be either a partial sequence or a tRNA ligase-related protein involved in some process other than protein translation on the ribosome.

GO Terms:

Molecular Function:: nucleotide binding (GO:0000166)

Molecular Function:: aminoacyl-tRNA ligase activity (GO:0004812)

Molecular Function:: ATP binding (GO:0005524)

Biological Process:: tRNA aminoacylation for protein translation (GO:0006418)

Date:: 2024-04-03

Family Accession:: NF012796.4
Method:: HMM

Select item 3479663.

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Family Accession:

Select item 3468624.

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Family Accession:

Select item 3169115.

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Family Accession:

Select item 3159006.

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Family Accession:

Select item 2963247.

serine--tRNA ligase

Gene:: serS

Date:: 2020-12-30

Family Accession:: NBR013667
Method:: BlastRule

Select item 2306838.

serine--tRNA ligase

serine--tRNA ligase catalyzes the attachment of serine to tRNA(Ser)

GO Terms:

Cellular Component:: cytoplasm (GO:0005737)

Molecular Function:: ATP binding (GO:0005524)

Biological Process:: seryl-tRNA aminoacylation (GO:0006434)

Molecular Function:: serine-tRNA ligase activity (GO:0004828)

Biological Process:: selenocysteine biosynthetic process (GO:0016260)

Biological Process:: obsolete selenocysteinyl-tRNA(Sec) biosynthetic process (GO:0097056)

Date:: 2023-03-15

Family Accession:: 11480938
Method:: Sparcle

Select item 1445299.

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Family Accession:

Select item 14441910.

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Family Accession:

Select item 1916311.

serine--tRNA ligase

This HMM represents the serine--tRNA ligase found in most organisms. It is a class II tRNA ligase. The seryl-tRNA synthetases of two model archaeal species, Methanococcus jannaschii and Methanobacterium thermoautotrophicum, differ considerably and are included in a different model.

Gene:: serS

GO Terms:

Molecular Function:: nucleotide binding (GO:0000166)

Molecular Function:: serine-tRNA ligase activity (GO:0004828)

Molecular Function:: ATP binding (GO:0005524)

Biological Process:: seryl-tRNA aminoacylation (GO:0006434)

Date:: 2024-05-15

Family Accession:: TIGR00414.1
Method:: HMM

Select item 419712.

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Family Accession:

Select item 348313.

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Family Accession:

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