Protein Family Models

This family forms a component of the de novo purine biosynthesis pathway. [1]. 10071207. Isolation and characterization of a purC(orf)QLF operon from. Lactococcus [correction of Lactobacillus] lactis MG1614.. Peltonen T, Mantsala P;. Mol Gen Genet 1999;261:31-41. (from Pfam)

Date:

2024-08-14

phosphoribosylformylglycinamidine synthase subunit PurS catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate

Date:

2018-05-01

With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway

Gene:

purS

Date:

2020-10-26

phosphoribosylformylglycinamidine synthase subunit PurS catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate

Date:

2018-05-01

In species such as Bacillus subtilis in which FGAM synthetase is split into two ORFs purL and purQ, this small protein, previously called yexA, is required for FGAM synthetase activity. Although the article does not make it clear whether this is a subunit or an accessory protein, it is encoded as part of the operon, which suggests stochiometric amounts, = subunit.

Gene:

purS

Date:

2021-04-27