Protein Family Models

This family consists of several bacterial thiazole biosynthesis protein G sequences. ThiG , together with ThiF and ThiH, is proposed to be involved in the synthesis of 4-methyl-5-(b-hydroxyethyl)thiazole (THZ) which is an intermediate in the thiazole production pathway [1]. This family also includes triosephosphate isomerase and pyridoxal 5'-phosphate synthase subunit PdxS. [1]. 9371431. Expression of thiamin biosynthetic genes (thiCOGE) and. production of symbiotic terminal oxidase cbb3 in Rhizobium etli.. Miranda-Rios J, Morera C, Taboada H, Davalos A, Encarnacion S,. Mora J, Soberon M;. J Bacteriol 1997;179:6887-6893. (from Pfam)

Date:

2024-08-14

Members of this family are enzymes involved in a new pathway of pyridoxine/pyridoxal 5-phosphate biosynthesis [1]. This family was formerly known as UPF0019. [1]. 8955308. A stationary-phase gene in Saccharomyces cerevisiae is a member. of a novel, highly conserved gene family.. Braun EL, Fuge EK, Padilla PA, Werner-Washburne M;. J Bacteriol 1996;178:6865-6872.. [2]. 10430950. A highly conserved sequence is a novel gene involved in de novo. vitamin B6 biosynthesis.. Ehrenshaft M, Bilski P, Li MY, Chignell CF, Daub ME;. Proc Natl Acad Sci U S A 1999;96:9374-9378.. [3]. 10438537. The extremely conserved pyroA gene of Aspergillus nidulans is. required for pyridoxine synthesis and is required indirectly for. resistance to photosensitizers.. Osmani AH, May GS, Osmani SA;. J Biol Chem 1999;274:23565-23569. (from Pfam)

Date:

2024-08-14

Gene:

pdxS

Date:

2020-12-30

PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate

Gene:

pdxS

Date:

2021-07-30

pyridoxal 5'-phosphate synthase subunit PdxS combines ammonia with five- and three-carbon phosphosugars to form pyridoxal 5'-phosphate (PLP)

Date:

2015-08-28

This protein had been believed to be a singlet oxygen resistance protein. Subsequent work showed that it is a protein of pyridoxine (vitamin B6) biosynthesis, and that pyridoxine quenches the highly toxic singlet form of oxygen produced by light in the presence of certain chemicals.

Gene:

pdxS

Date:

2024-06-26