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RsmG family class I SAM-dependent methyltransferase
Most member of this methyltransferase family are the 16S RNA G527 methyltransferase RsmG, previously known as GidB (glucose inhibited division protein B).
16S rRNA (guanine(527)-N(7))-methyltransferase RsmG
16S rRNA (guanine(527)-N(7))-methyltransferase RsmG specifically methylates the N7 position of guanine in position 527 of 16S rRNA; requires the intact 30S subunit for methylation
RsmG was previously called GidB (glucose-inhibited division protein B). It is present and a single copy in nearly all complete eubacterial genomes. It is missing only from some obligate intracellular species of various lineages (Chlamydiae, Ehrlichia, Wolbachia, Anaplasma, Buchnera, etc.). RsmG shows a methytransferase fold in its the crystal structure, and acts as a 7-methylguanosine (m(7)G) methyltransferase, apparently specific to 16S rRNA.
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