Protein Family Models

This domain consists of 4 beta strands and two alpha helices which make up the dimerisation surface of members of the M20 family of peptidases [1]. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification [2]. Family M20 are Glutamate carboxypeptidases. Peptidase family M25 contains X-His dipeptidases. [1]. 9083113. Crystal structure of carboxypeptidase G2, a bacterial enzyme. with applications in cancer therapy.. Rowsell S, Pauptit RA, Tucker AD, Melton RG, Blow DM, Brick P;. Structure 1997;5:337-347.. [2]. 7674922. Evolutionary families of metallopeptidases.. Rawlings ND, Barrett AJ;. Meth Enzymol 1995;248:183-228. (from Pfam)

Date:

2024-08-14

This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification [1]. Family M20 are Glutamate carboxypeptidases. Peptidase family M25 contains X-His dipeptidases. [1]. 7674922. Evolutionary families of metallopeptidases.. Rawlings ND, Barrett AJ;. Meth Enzymol 1995;248:183-228. (from Pfam)

Date:

2024-08-14

Gene:

ylmB

Date:

2020-08-13

Catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine

Date:

2021-11-04

This group of sequences contains annotations for both acetylornithine deacetylase and succinyl-diaminopimelate desuccinylase, but does not contain any members with experimental characterization. Bacillus, Staphylococcus and Sulfolobus species contain multiple hits to this subfamily and each may have a separate activity. Determining which is which must await further laboratory research.

Date:

2021-10-27

peptidase M20 family protein similar to Bacillus subtilis N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase that catalyzes the deformylation of the formylaminopyrimidine N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) to give the corresponding aminopyrimidine

Date:

2020-10-09