Protein Family Models for Protein (Select 810369244) - Protein Family Models

Select item 4226261.

This family represents the periplasmic core domain found in a variety of ABC transporters. The structure of this family has been solved for the MacB protein [1]. Some structural similarity was found to the periplasmic domain of the AcrB multidrug efflux transporter. [1]. 19432486. Crystal structure of the periplasmic region of MacB, a. noncanonic ABC transporter.. Xu Y, Sim SH, Nam KH, Jin XL, Kim HM, Hwang KY, Lee K, Ha NC;. Biochemistry. 2009;48:5218-5225. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024116.5
Method:: HMM

Select item 4126752.

FtsX-like permease family protein

This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices. (from Pfam)

GO Terms:

Cellular Component:: membrane (GO:0016020)

Date:: 2024-08-14

Family Accession:: NF014717.5
Method:: HMM

Select item 4111433.

ATP-binding cassette domain-containing protein

ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain Pfam:PF00664. These four domains may belong to a single polypeptide as in Swiss:P13569, or belong in different polypeptide chains. [1]. 1864505. Homology between proteins controlling Streptomyces fradiae. tylosin resistance and ATP-binding transport.. Rosteck PR Jr, Reynolds PA, Hershberger CL;. Gene 1991;102:27-32.. [2]. 1977073. Structure and function of haemolysin B,P-glycoprotein and other. members of a novel family of membrane translocators.. Blight MA, Holland IB;. Mol Microbiol 1990;4:873-880.. [3]. 2229036. Binding protein-dependent transport systems.. Higgins CF, Hyde SC, Mimmack MM, Gileadi U, Gill DR, Gallagher. MP;. J Bioenerg Biomembr 1990;22:571-592.. [4]. 9872322. Crystal structure of the ATP-binding subunit of an ABC. transporter.. Hung LW, Wang IX, Nikaido K, Liu PQ, Ames GF, Kim SH;. Nature 1998;396:703-707. (from Pfam)

GO Terms:

Molecular Function:: ATP binding (GO:0005524)

Date:: 2024-08-14

Family Accession:: NF012235.5
Method:: HMM

Select item 3989864.