Protein Family Models

This is a sensor domain that recognises O2, CO and NO (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). (from Pfam)

Date:

2024-08-14

The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs [4]. The PAS fold appears in archaea, eubacteria and eukarya. This domain is associated to signalling systems and works as a signal sensor domain. It recognises differently substituted aromatic hydrocarbons, oxygen, different dodecanoic acids, autoinducers, 3,5-dimethyl-pyrazin-2-ol and N-alanyl-aminoacetone (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). [1]. 9301332. PAS domain S-boxes in archaea, bacteria and sensors for oxygen. and redox.. Zhulin IB, Taylor BL, Dixon R;. Trends Biochem Sci 1997;22:331-333.. [2]. 7756254. 1.4 A structure of photoactive yellow protein, a cytosolic. photoreceptor: unusual fold, active site, and chromophore.. Borgstahl GE, Williams DR, Getzoff ED;. Biochemistry 1995;34:6278-6287.. [3]. 9382818. PAS: a multifunctional domain family comes to light.. Ponting CP, Aravind L;. Curr Biol 1997;7:674-677.. [4]. 15009198. The PAS fold: a redefination of the PAS domain based upon. structural prediction.. Hefti MH, Francoijs KJ, de Vries SC, Dixon R, Vervoort J;. Eur J Biochem 2004;271:1198-1208. (from Pfam)

Date:

2024-08-14

This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90. [1]. 18361456. Crystal structure of a novel non-Pfam protein AF1514 from. Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray. source.. Li Y, Bahti P, Shaw N, Song G, Chen S, Zhang X, Zhang M, Cheng. C, Yin J, Zhu JY, Zhang H, Che D, Xu H, Abbas A, Wang BC, Liu. ZJ;. Proteins 2008;71:2109-13. (from Pfam)

Date:

2024-08-14

Date:

2024-08-14

Dimerisation and phospho-acceptor domain of histidine kinases. [1]. 9989504. Structure of CheA, a signal-transducing histidine kinase.. Bilwes AM, Alex LA, Crane BR, Simon MI;. Cell 1999;96:131-141.. [2]. 18361456. Crystal structure of a novel non-Pfam protein AF1514 from. Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray. source.. Li Y, Bahti P, Shaw N, Song G, Chen S, Zhang X, Zhang M, Cheng. C, Yin J, Zhu JY, Zhang H, Che D, Xu H, Abbas A, Wang BC, Liu. ZJ;. Proteins 2008;71:2109-13. (from Pfam)

Date:

2024-08-14

The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs [4]. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). [1]. 9301332. PAS domain S-boxes in archaea, bacteria and sensors for oxygen. and redox.. Zhulin IB, Taylor BL, Dixon R;. Trends Biochem Sci 1997;22:331-333.. [2]. 7756254. 1.4 A structure of photoactive yellow protein, a cytosolic. photoreceptor: unusual fold, active site, and chromophore.. Borgstahl GE, Williams DR, Getzoff ED;. Biochemistry 1995;34:6278-6287.. [3]. 9382818. PAS: a multifunctional domain family comes to light.. Ponting CP, Aravind L;. Curr Biol 1997;7:674-677.. [4]. 15009198. The PAS fold: a redefination of the PAS domain based upon. structural prediction.. Hefti MH, Francoijs KJ, de Vries SC, Dixon R, Vervoort J;. Eur J Biochem 2004;271:1198-1208. (from Pfam)

Date:

2024-08-14

Gene:

pnpS

Date:

2024-06-07

sensor histidine kinase with a HAMP signaling domain, part of a two-component regulatory system, functions as a protein kinase that phosphorylates a target protein in response to external signals

Date:

2020-02-26