Protein Family Models for Protein (Select 906970013) - Protein Family Models

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Items: 7

Select item 4196331.

Spo0E family sporulation regulatory protein-aspartic acid phosphatase

Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure [1]. [1]. 17001075. Structural Characterization of Spo0E-like Protein-aspartic Acid. Phosphatases That Regulate Sporulation in Bacilli.. Grenha R, Rzechorzek NJ, Brannigan JA, de Jong RN, Ab E, Diercks. T, Truffault V, Ladds JC, Fogg MJ, Bongiorni C, Perego M,. Kaptein R, Wilson KS, Folkers GE, Wilkinson AJ;. J Biol Chem. 2006;281:37993-38003. (from Pfam)

GO Terms:

Biological Process:: regulation of sporulation (GO:0043937)

Date:: 2024-08-14

Family Accession:: NF020945.5
Method:: HMM

Select item 3960312.

new record, indexing in progress

Family Accession:

Select item 3596913.

new record, indexing in progress

Family Accession:

Select item 3243204.

new record, indexing in progress

Family Accession:

Select item 2130415.

aspartyl-phosphate phosphatase Spo0E family protein

aspartyl-phosphate phosphatase Spo0E specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation