Protein Family Models for Protein (Select 944520140) - Protein Family Models

Select item 4225261.

This entry includes a wide variety of AAA domains, including some that have lost essential nucleotide binding residues in the P-loop. This domain is found in Lon proteases from archaea and bacteria [1]. [1]. 23897463. Structures of an ATP-independent Lon-like protease and its. complexes with covalent inhibitors.. Liao JH, Ihara K, Kuo CI, Huang KF, Wakatsuki S, Wu SH, Chang. CI;. Acta Crystallogr D Biol Crystallogr. 2013;69:1395-1402. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF025038.5
Method:: HMM

Select item 4157762.

S16 family serine protease

The Lon serine proteases must hydrolyse ATP to degrade protein substrates. In Escherichia coli, these proteases are involved in turnover of intracellular proteins, including abnormal proteins following heat-shock. The active site for protease activity resides in a C-terminal domain. The Lon proteases are classified as family S16 in Merops. [1]. 12208506. Domain structure and ATP-induced conformational changes in. Escherichia coli protease Lon revealed by limited proteolysis. and autolysis.. Vasilyeva OV, Kolygo KB, Leonova YF, Potapenko NA, Ovchinnikova. TV;. FEBS Lett 2002;526:66-70. (from Pfam)

GO Terms:

Molecular Function:: ATP-dependent peptidase activity (GO:0004176)

Molecular Function:: serine-type endopeptidase activity (GO:0004252)

Biological Process:: proteolysis (GO:0006508)

Date:: 2024-08-14

Family Accession:: NF017200.5
Method:: HMM

Select item 4005003.