Protein Family Models for Protein (Select 968557893) - Protein Family Models

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Links from Protein

Items: 6

Select item 4113141.

orotidine 5'-phosphate decarboxylase / HUMPS family protein

This family includes Orotidine 5'-phosphate decarboxylase enzymes EC:4.1.1.23 that are involved in the final step of pyrimidine biosynthesis. The family also includes enzymes such as hexulose-6-phosphate synthase. This family appears to be distantly related to Pfam:PF00834. (from Pfam)

GO Terms:

Molecular Function:: orotidine-5'-phosphate decarboxylase activity (GO:0004590)

Biological Process:: 'de novo' pyrimidine nucleobase biosynthetic process (GO:0006207)

Date:: 2024-08-14

Family Accession:: NF012441.5
Method:: HMM

Select item 3892572.

new record, indexing in progress

Family Accession:

Select item 3465993.

new record, indexing in progress

Family Accession:

Select item 1959064.

orotidine 5'-phosphate decarboxylase

Orotidine 5'-phosphate decarboxylase (ODCase) decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway.

Date:: 2023-03-02

Family Accession:: 10791852
Method:: Sparcle

Select item 1728045.

orotidine-5'-phosphate decarboxylase

Type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide

Gene:: pyrF

GO Terms:

Molecular Function:: orotidine-5'-phosphate decarboxylase activity (GO:0004590)

Biological Process:: 'de novo' pyrimidine nucleobase biosynthetic process (GO:0006207)

Biological Process:: 'de novo' UMP biosynthetic process (GO:0044205)

Date:: 2021-07-22

Family Accession:: NF001273.0
Method:: HMM

Select item 1427926.

orotidine-5'-phosphate decarboxylase

This model represents orotidine 5'-monophosphate decarboxylase, the PyrF protein of pyrimidine nucleotide biosynthesis. In many eukaryotes, the region hit by this model is part of a multifunctional protein.