Complete response to topotecan of recurrent fallopian tube carcinoma

Gynecol Oncol. 2000 Jan;76(1):128-9. doi: 10.1006/gyno.1999.5630.

Abstract

Objective: To describe the first complete response of recurrent Fallopian tube carcinoma to topotecan.

Methods: A patient with recurrent Fallopian tube carcinoma previously treated with paclitaxel (Taxol) and carboplatin is described.

Results: This patient demonstrated a complete clinical response to topotecan. Radiographic and CA-125 measurements were used to determine response. Response was noted after four cycles and a complete response demonstrated after six treatments.

Conclusion: Topotecan appears active in recurrent Fallopian tube carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • CA-125 Antigen / analysis
  • Fallopian Tube Neoplasms / drug therapy*
  • Fallopian Tube Neoplasms / pathology
  • Female
  • Humans
  • Topotecan / pharmacology
  • Topotecan / therapeutic use*
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • CA-125 Antigen
  • Topotecan