11073942,20381137,22424946,22575674,23394946,25259925,25561175,25567906[uid] - Search Results

Year	Number of Results
2000	1
2001	1
2010	1
2012	2
2013	1
2014	1
2015	2
2024	0

1

Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.

Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T. Sekiguchi T, et al. J Biol Chem. 2001 Mar 9;276(10):7246-57. doi: 10.1074/jbc.M004389200. Epub 2000 Nov 9. J Biol Chem. 2001. PMID: 11073942 Free article.

2

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. Sancak Y, et al. Cell. 2010 Apr 16;141(2):290-303. doi: 10.1016/j.cell.2010.02.024. Epub 2010 Apr 8. Cell. 2010. PMID: 20381137 Free PMC article.

3

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.

Han JM, Jeong SJ, Park MC, Kim G, Kwon NH, Kim HK, Ha SH, Ryu SH, Kim S. Han JM, et al. Cell. 2012 Apr 13;149(2):410-24. doi: 10.1016/j.cell.2012.02.044. Epub 2012 Mar 15. Cell. 2012. PMID: 22424946 Free article.

4

SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.

Kim YM, Stone M, Hwang TH, Kim YG, Dunlevy JR, Griffin TJ, Kim DH. Kim YM, et al. Mol Cell. 2012 Jun 29;46(6):833-46. doi: 10.1016/j.molcel.2012.04.007. Epub 2012 May 9. Mol Cell. 2012. PMID: 22575674 Free PMC article.

5

mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.

Cang C, Zhou Y, Navarro B, Seo YJ, Aranda K, Shi L, Battaglia-Hsu S, Nissim I, Clapham DE, Ren D. Cang C, et al. Cell. 2013 Feb 14;152(4):778-790. doi: 10.1016/j.cell.2013.01.023. Epub 2013 Feb 7. Cell. 2013. PMID: 23394946 Free PMC article.

6

Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.

Peng M, Yin N, Li MO. Peng M, et al. Cell. 2014 Sep 25;159(1):122-133. doi: 10.1016/j.cell.2014.08.038. Cell. 2014. PMID: 25259925 Free PMC article.

7

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.

Rebsamen M, Pochini L, Stasyk T, de Araújo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G. Rebsamen M, et al. Nature. 2015 Mar 26;519(7544):477-81. doi: 10.1038/nature14107. Epub 2015 Jan 7. Nature. 2015. PMID: 25561175 Free PMC article.

8

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.

Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM. Wang S, et al. Science. 2015 Jan 9;347(6218):188-94. doi: 10.1126/science.1257132. Epub 2015 Jan 7. Science. 2015. PMID: 25567906 Free PMC article.

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