Metachronous Wilms tumor associated with pulmonary embolism: how can we detect these cases early? A case report and literature review

Pediatr Hematol Oncol. 2003 Jan-Feb;20(1):55-63.

Abstract

A 4-year-old girl developed right metachronous Wilms tumor 2 years after completing treatment for a left-sided stage I Wilms tumor. The original treatment included 7 weeks of chemotherapy, delayed nephrectomy, and another 3 weeks of chemotherapy. The metachronous tumor on the right side extended into the inferior vena cava and right atrium. She developed pulmonary embolism as a result. She received chemotherapy and developed liquifaction of the tumor and toxic shock. She also had surgery. The patient is alive 3 years after the original diagnosis and 10 months after the relapse. The authors report this unusual case and discuss whether these cases can be identified early.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Child, Preschool
  • Female
  • Humans
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / surgery
  • Neoplasms, Second Primary / complications*
  • Neoplasms, Second Primary / diagnosis
  • Neoplasms, Second Primary / therapy
  • Nephrectomy
  • Pulmonary Embolism / etiology*
  • Wilms Tumor / complications*
  • Wilms Tumor / diagnosis
  • Wilms Tumor / therapy