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INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases.
Biochem J. 2006 Jul 1;397(1):169-77. doi: 10.1042/BJ20051669.
Biochem J. 2006.
PMID: 16569215
Free PMC article.
Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription.
Wang HW, Muguira M, Liu WD, Zhang T, Chen C, Aucoin R, Breslin MB, Lan MS.
Wang HW, et al.
J Endocrinol. 2008 Jul;198(1):29-39. doi: 10.1677/JOE-08-0001. Epub 2008 Apr 16.
J Endocrinol. 2008.
PMID: 18417529
Free PMC article.
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