Eosinophilic angiocentric fibrosis

J Craniofac Surg. 2006 Jul;17(4):812-4. doi: 10.1097/00001665-200607000-00040.

Abstract

Eosinophilic angiocentric fibrosis (EAF) is a rare disease of the sinonasal tract, with histologic characteristic features like thick collagen bundles whirling around vessels in a fibrotic stroma with inflammatory cells rich in eosinophils. The Authors present a case of a 31-year-old man with bilateral nasal obstruction with no history of allergies or other systemic disease. The patient underwent a septoplasty with symptoms relieving. An EAF diagnosis was made. Differential diagnosis must rule out other lesions that may mimic EAF such as granuloma faciale, Kimura disease, Wegener granulomatosis, Churg-Strauss syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Eosinophilia / diagnosis*
  • Fibrosis
  • Follow-Up Studies
  • Humans
  • Male
  • Nasal Obstruction / diagnosis
  • Nasal Polyps / diagnosis
  • Nose Diseases / diagnosis*