Neurological and psychiatric aspects of corpus callosum genesis

Psychiatr Danub. 2010 Jun;22(2):282-5.

Abstract

This article reports the case of a patient with partial agenesis of the corpus callosum manifested with corpus callosum syndrome together with signs of brain hemispheres dysfunction: mental impairment, epilepsy and pyramidal signs. The patient's malformation is combined with left-handedness while signs of callosal disconnection are not present. Mild cognitive impairment and late epilepsy onset require a multidisciplinary approach since the patient also displays elements of central nervous system malformations.

Publication types

  • Case Reports

MeSH terms

  • Acrocallosal Syndrome / diagnosis*
  • Acrocallosal Syndrome / drug therapy
  • Acrocallosal Syndrome / physiopathology
  • Acrocallosal Syndrome / psychology*
  • Adult
  • Amnesia / diagnosis*
  • Amnesia / drug therapy
  • Amnesia / physiopathology
  • Amnesia / psychology
  • Anticonvulsants / therapeutic use
  • Apraxias / diagnosis*
  • Apraxias / drug therapy
  • Apraxias / physiopathology
  • Apraxias / psychology
  • Epilepsy, Generalized / diagnosis*
  • Epilepsy, Generalized / drug therapy
  • Epilepsy, Generalized / physiopathology
  • Epilepsy, Generalized / psychology
  • Functional Laterality / physiology
  • Humans
  • Lamotrigine
  • Leg Length Inequality / diagnosis*
  • Leg Length Inequality / physiopathology
  • Leg Length Inequality / psychology
  • Magnetic Resonance Imaging
  • Male
  • Neurologic Examination
  • Neuropsychological Tests
  • Paranoid Disorders / diagnosis*
  • Paranoid Disorders / drug therapy
  • Paranoid Disorders / physiopathology
  • Paranoid Disorders / psychology
  • Pyramidal Tracts / physiopathology
  • Syndrome
  • Triazines / therapeutic use

Substances

  • Anticonvulsants
  • Triazines
  • Lamotrigine