Inflammatory neuropathies

Semin Neurol. 2010 Sep;30(4):356-64. doi: 10.1055/s-0030-1267279. Epub 2010 Oct 12.

Abstract

Inflammatory neuropathies are acquired disorders of peripheral nerves and occasionally of the central nervous system that can affect individuals at any age. The course can be monophasic, relapsing, or progressive. Inflammatory neuropathies are classified as acute or chronic. The acute form reaches a nadir by 4 weeks and the chronic form over 8 weeks or greater. The most common example of an acute inflammatory neuropathy is acute inflammatory demyelinating polyradiculoneuropathy (AIDP), which is part of the Guillain-Barré syndrome (GBS). The most common chronic inflammatory neuropathy is chronic inflammatory demyelinating polyradiculopathy (CIDP). Other chronic inflammatory neuropathies are multifocal motor neuropathy (MMN) and the Lewis-Sumner syndrome. The Fisher syndrome and Bickerstaff brainstem encephalitis occur acutely and have clinical overlap with AIDP.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Guillain-Barre Syndrome / diagnosis
  • Guillain-Barre Syndrome / pathology
  • Humans
  • Peripheral Nervous System Diseases / diagnosis*
  • Peripheral Nervous System Diseases / pathology*
  • Polyradiculoneuropathy / diagnosis*
  • Polyradiculoneuropathy / pathology*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / diagnosis
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / pathology