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Heterocomplexes of mannose-binding lectin and the pentraxins PTX3 or serum amyloid P component trigger cross-activation of the complement system.
J Biol Chem. 2011 Feb 4;286(5):3405-17. doi: 10.1074/jbc.M110.190637. Epub 2010 Nov 24.
J Biol Chem. 2011.
PMID: 21106539
Free PMC article.
Mannan-binding lectin directly interacts with Toll-like receptor 4 and suppresses lipopolysaccharide-induced inflammatory cytokine secretion from THP-1 cells.
Wang M, Chen Y, Zhang Y, Zhang L, Lu X, Chen Z.
Wang M, et al.
Cell Mol Immunol. 2011 May;8(3):265-75. doi: 10.1038/cmi.2011.1. Epub 2011 Mar 7.
Cell Mol Immunol. 2011.
PMID: 21383675
Free PMC article.
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MASP interactions with plasma-derived MBL.
Laursen IA, Thielens NM, Christiansen M, Houen G.
Laursen IA, et al.
Mol Immunol. 2012 Sep;52(2):79-87. doi: 10.1016/j.molimm.2012.04.014. Epub 2012 May 18.
Mol Immunol. 2012.
PMID: 22607836
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Structural insights into the initiating complex of the lectin pathway of complement activation.
Kjaer TR, Le le TM, Pedersen JS, Sander B, Golas MM, Jensenius JC, Andersen GR, Thiel S.
Kjaer TR, et al.
Structure. 2015 Feb 3;23(2):342-51. doi: 10.1016/j.str.2014.10.024. Epub 2015 Jan 8.
Structure. 2015.
PMID: 25579818
Free article.
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Oligomerization of Mannan-binding Lectin Dictates Binding Properties and Complement Activation.
Kjaer TR, Jensen L, Hansen A, Dani R, Jensenius JC, Dobó J, Gál P, Thiel S.
Kjaer TR, et al.
Scand J Immunol. 2016 Jul;84(1):12-9. doi: 10.1111/sji.12441.
Scand J Immunol. 2016.
PMID: 27104295
Free article.
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